Spero Therapeutics, Inc. (SPRO)

Spero Therapeutics, Inc. at a glance — key fundamentals, SEC filings, insider buying and selling, and earnings dates.

Spero Therapeutics, Inc. (SPRO) is a Biotechnology company based in US with a market capitalization of $79.9M. Revenue grew 24.3% year-over-year and free cash flow was negative at -$12.6M. This page tracks SPRO's SEC filings, insider buying and selling, earnings dates, and key fundamentals in one place.

US · 32 employees · IPO Nov 2, 2017

Valuation

Valuation & price

$2.79as of May 17, 2026· -6.4% vs 52w high

19.2

P/E ratio

Latest-FY diluted EPS

1.35

P/B ratio

Market cap ÷ book equity

Dividend yield

Price — last 12 months

$2.91$2.05$1.19Jul 25Jan 26Jul 26
$1.1652-week range$2.98
Loading valuation history…

Fundamentals

Key fundamentals

$79.9M

Market cap

24.3%

Revenue growth (YoY)

100.0%

Gross margin

-$12.6M

Free cash flow (USD)

-$37.4M

Net debt

Net cash position

3.7%

Share dilution

1/5

Graham criteria passed

Defensive-investor screen

Healthcare

Sector

Trajectory

Long-term trends

Revenue by year

20162025

$335K$59.6M

Free cash flow by year

20162025

-$29.8M-$12.6M

Gross margin by year

20212025

100.0%100.0%

Value screen

Graham defensive-investor tests

Computing the scorecard — refreshing any stale inputs…

0

Insider buys · 90 days

1

Insider sells · 90 days

Earnings

Last report: 10-Q filed May 13, 2026

Next expected: not yet scheduled

On the tape

Recent SEC & insider activity

  • 8-K eventJul 14, 2026Filing

    License Agreement Signed

  • 8-K eventJun 25, 2026Filing

    Stockholder Meeting Results

  • 8-K eventJun 22, 2026Filing

    FDA Approval

  • 8-K eventMay 13, 2026Filing

    Earnings Release

  • Quarterly reportMay 13, 2026Filing

    10-Q Filed

  • Insider sellMay 6, 2026Filing

    Insider Sell $63KRajavelu Esther · See Remarks · $63.4K

Questions

Frequently asked questions

What is Spero Therapeutics, Inc.'s market cap?

Spero Therapeutics, Inc. (SPRO) has a market capitalization of $79.9M.

What is SPRO's P/E ratio?

SPRO trades at a price-to-earnings ratio of 19.2, based on its latest fiscal-year diluted earnings per share and the most recent cached price.

What is SPRO's price-to-book (P/B) ratio?

SPRO trades at 1.35 times book value per share.

Are insiders buying SPRO stock?

SEC Form 4 filings show no open-market insider buys at Spero Therapeutics, Inc. in the last 90 days (1 sell).

Same arena

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Timeline

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News

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Data: SEC EDGAR filings and cached fundamental data; prices and ratios use the most recent cached quote and statements (may lag by up to a day). Educational and research purposes only. Not investment advice.